TY - GEN AU - Bard-Chapeau,Emilie A AU - Szumska,Dorota AU - Jacob,Bindya AU - Chua,Belinda Q L AU - Chatterjee,Gouri C AU - Zhang,Yi AU - Ward,Jerrold M AU - Urun,Fatma AU - Kinameri,Emi AU - Vincent,Stéphane D AU - Ahmed,Sayadi AU - Bhattacharya,Shoumo AU - Osato,Motomi AU - Perkins,Archibald S AU - Moore,Adrian W AU - Jenkins,Nancy A AU - Copeland,Neal G TI - Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects SN - 1932-6203 PY - 2014///1029 KW - Alleles KW - Animals KW - Animals, Newborn KW - Base Sequence KW - Bone Marrow KW - pathology KW - DNA-Binding Proteins KW - chemistry KW - Disease Models, Animal KW - Exons KW - Gene Deletion KW - Gene Expression Regulation, Developmental KW - Genes, Lethal KW - Genetic Association Studies KW - Heart Defects, Congenital KW - genetics KW - Hematopoiesis KW - Hematopoietic Stem Cells KW - metabolism KW - Immunophenotyping KW - MDS1 and EVI1 Complex Locus Protein KW - Mice KW - Mice, Knockout KW - Molecular Sequence Data KW - Mutation KW - Phenotype KW - Proto-Oncogenes KW - Sequence Alignment KW - Severity of Illness Index KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0089397 ER -