TY - GEN AU - Bai,R AU - Pettit,G R AU - Hamel,E TI - Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain SN - 0006-2952 PY - 1990///0719 KW - Amino Acid Sequence KW - Animals KW - Antibiotics, Antineoplastic KW - pharmacology KW - Aziridines KW - pharmacokinetics KW - Cell Division KW - drug effects KW - Cell Survival KW - Depsipeptides KW - Diamines KW - Drug Interactions KW - Guanosine Triphosphate KW - metabolism KW - Mice KW - Mitotic Index KW - Molecular Sequence Data KW - Oligopeptides KW - Organophosphorus Compounds KW - Thiazoles KW - Tubulin KW - Tumor Cells, Cultured KW - Vinca Alkaloids KW - Vincristine N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1016/0006-2952(90)90613-p ER -