Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome. [electronic resource]
- Science (New York, N.Y.) Feb 2014
- 1002-5 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1095-9203
10.1126/science.1245831 doi
Animals Cell Line DNA Methylation Embryonic Stem Cells--metabolism Fragile X Mental Retardation Protein--genetics Fragile X Syndrome--genetics Gene Silencing Humans Mice Mice, Inbred NOD Mice, SCID Neurons--metabolism Nuclear Proteins--genetics Promoter Regions, Genetic--genetics RNA, Messenger--genetics RNA, Small Interfering--genetics Trinucleotide Repeats--genetics