TY - GEN AU - Zhang,Yilan AU - Luo,Rui AU - Chen,Yi AU - Ke,Xue AU - Hu,Danrong AU - Han,Miaomiao TI - Application of carrier and plasticizer to improve the dissolution and bioavailability of poorly water-soluble baicalein by hot melt extrusion SN - 1530-9932 PY - 2015///0720 KW - Administration, Oral KW - Animals KW - Biological Availability KW - Calorimetry, Differential Scanning KW - Chemistry, Pharmaceutical KW - Crystallography, X-Ray KW - Dogs KW - Drug Carriers KW - Drug Stability KW - Flavanones KW - administration & dosage KW - Hot Temperature KW - Male KW - Models, Chemical KW - Phase Transition KW - Plasticizers KW - chemistry KW - Polyethylene Glycols KW - Polymethacrylic Acids KW - Powder Diffraction KW - Pyrrolidines KW - Solubility KW - Spectroscopy, Fourier Transform Infrared KW - Technology, Pharmaceutical KW - methods KW - Vinyl Compounds KW - Water N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1208/s12249-013-0071-x ER -