TY  - GEN
AU  - Plaza-Menacho,Iván
AU  - Barnouin,Karin
AU  - Goodman,Kerry
AU  - Martínez-Torres,Rubén J
AU  - Borg,Annabel
AU  - Murray-Rust,Judith
AU  - Mouilleron,Stephane
AU  - Knowles,Phillip
AU  - McDonald,Neil Q
TI  - Oncogenic RET kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans
SN  - 1097-4164
PY  - 2014///0428
KW  - Adenosine Triphosphate
KW  - chemistry
KW  - Amino Acid Sequence
KW  - Animals
KW  - Binding Sites
KW  - Crystallography, X-Ray
KW  - Gene Expression Regulation, Enzymologic
KW  - Humans
KW  - Insecta
KW  - Ligands
KW  - Mass Spectrometry
KW  - Molecular Sequence Data
KW  - Mutation
KW  - Phosphorylation
KW  - Protein Structure, Tertiary
KW  - Proto-Oncogene Proteins c-ret
KW  - Recombinant Proteins
KW  - Sequence Homology, Amino Acid
KW  - Substrate Specificity
KW  - Time Factors
KW  - Tyrosine
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.molcel.2014.01.015
ER  -