TY  - GEN
AU  - Cheng,J
AU  - Fan,Y-H
AU  - Xu,X
AU  - Zhang,H
AU  - Dou,J
AU  - Tang,Y
AU  - Zhong,X
AU  - Rojas,Y
AU  - Yu,Y
AU  - Zhao,Y
AU  - Vasudevan,S A
AU  - Zhang,H
AU  - Nuchtern,J G
AU  - Kim,E S
AU  - Chen,X
AU  - Lu,F
AU  - Yang,J
TI  - A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways
SN  - 2041-4889
PY  - 2014///1021
KW  - Active Transport, Cell Nucleus
KW  - drug effects
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Activation
KW  - Enzyme Inhibitors
KW  - Female
KW  - HEK293 Cells
KW  - Humans
KW  - JNK Mitogen-Activated Protein Kinases
KW  - antagonists & inhibitors
KW  - Mice
KW  - Mice, Nude
KW  - Mutation
KW  - Neuroblastoma
KW  - drug therapy
KW  - Protein Kinase Inhibitors
KW  - Signal Transduction
KW  - Time Factors
KW  - Transfection
KW  - Tumor Burden
KW  - Tumor Suppressor Protein p53
KW  - genetics
KW  - Ubiquitin-Conjugating Enzymes
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/cddis.2014.54
ER  -