Mack, S C
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. [electronic resource]
- Nature Feb 2014
- 445-50 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1476-4687
10.1038/nature13108 doi
Animals
Brain Neoplasms--drug therapy
CpG Islands--genetics
DNA Methylation--drug effects
Embryonic Stem Cells--metabolism
Ependymoma--drug therapy
Epigenesis, Genetic--genetics
Epigenomics
Female
Gene Expression Regulation, Neoplastic
Gene Silencing--drug effects
Histones--drug effects
Humans
Infant
Mice
Mice, Inbred NOD
Mice, SCID
Mutation--genetics
Phenotype
Polycomb Repressive Complex 2--metabolism
Prognosis
Rhombencephalon--pathology
Xenograft Model Antitumor Assays