Takai, Kentaro

Structure-based optimization of cyclopropyl urea derivatives as potent soluble epoxide hydrolase inhibitors for potential decrease of renal injury without hypotensive action. [electronic resource] - Bioorganic & medicinal chemistry Mar 2014 - 1548-57 p. digital

Publication Type: Journal Article

1464-3391

10.1016/j.bmc.2014.01.040 doi


Animals
Blood Pressure--drug effects
Epoxide Hydrolases--antagonists & inhibitors
Epoxy Compounds--pharmacology
Hypotension--drug therapy
Rats
Urea--analogs & derivatives