TY  - GEN
AU  - Mathieu,M G
AU  - Miles,A K
AU  - Ahmad,M
AU  - Buczek,M E
AU  - Pockley,A G
AU  - Rees,R C
AU  - Regad,T
TI  - The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1
SN  - 2041-4889
PY  - 2014///1021
KW  - ATP Binding Cassette Transporter, Subfamily B
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - metabolism
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - DEAD-box RNA Helicases
KW  - genetics
KW  - Drug Resistance, Neoplasm
KW  - Gene Expression Regulation, Enzymologic
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Interferon-alpha
KW  - Janus Kinase 1
KW  - Melanoma
KW  - drug therapy
KW  - Mice
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Neoplasm Proteins
KW  - Neoplastic Stem Cells
KW  - drug effects
KW  - Nuclear Proteins
KW  - Phosphorylation
KW  - Promyelocytic Leukemia Protein
KW  - RNA Interference
KW  - RNA, Messenger
KW  - STAT Transcription Factors
KW  - Signal Transduction
KW  - Skin Neoplasms
KW  - Spheroids, Cellular
KW  - Suppressor of Cytokine Signaling 1 Protein
KW  - Suppressor of Cytokine Signaling Proteins
KW  - TYK2 Kinase
KW  - Time Factors
KW  - Transcription Factors
KW  - Transfection
KW  - Tumor Burden
KW  - Tumor Suppressor Proteins
KW  - Ubiquitination
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/cddis.2014.29
ER  -