TY - GEN AU - Mao,Shuai AU - Wang,Yanting AU - Zhang,Minzhou AU - Hinek,Aleksander TI - Phytoestrogen, tanshinone IIA diminishes collagen deposition and stimulates new elastogenesis in cultures of human cardiac fibroblasts SN - 1090-2422 PY - 2014///0605 KW - Abietanes KW - pharmacology KW - Anti-Inflammatory Agents, Non-Steroidal KW - Cell Line KW - Collagen Type I KW - genetics KW - Cyclic AMP Response Element-Binding Protein KW - metabolism KW - Cyclic AMP-Dependent Protein Kinases KW - Down-Regulation KW - Elastic Tissue KW - Elastin KW - Enzyme Activation KW - drug effects KW - Extracellular Matrix KW - Humans KW - Matrix Metalloproteinase 1 KW - biosynthesis KW - Matrix Metalloproteinase 2 KW - Matrix Metalloproteinase 9 KW - Myocardial Infarction KW - Myocardium KW - Myocytes, Cardiac KW - Phosphorylation KW - Phytoestrogens KW - Protein Binding KW - Protein-Lysine 6-Oxidase KW - Receptors, Estrogen KW - Receptors, G-Protein-Coupled KW - Tropoelastin KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.yexcr.2014.02.001 ER -