Mao, Shuai
Phytoestrogen, tanshinone IIA diminishes collagen deposition and stimulates new elastogenesis in cultures of human cardiac fibroblasts. [electronic resource]
- Experimental cell research Apr 2014
- 189-197 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1090-2422
Standard No.: 10.1016/j.yexcr.2014.02.001 doi
Subjects--Topical Terms: Abietanes--pharmacology Anti-Inflammatory Agents, Non-Steroidal--pharmacology Cell Line Collagen Type I--genetics Cyclic AMP Response Element-Binding Protein--metabolism Cyclic AMP-Dependent Protein Kinases--metabolism Down-Regulation Elastic Tissue--metabolism Elastin--genetics Enzyme Activation--drug effects Extracellular Matrix--metabolism Humans Matrix Metalloproteinase 1--biosynthesis Matrix Metalloproteinase 2--biosynthesis Matrix Metalloproteinase 9--biosynthesis Myocardial Infarction--metabolism Myocardium Myocytes, Cardiac--drug effects Phosphorylation--drug effects Phytoestrogens--pharmacology Protein Binding--drug effects Protein-Lysine 6-Oxidase--biosynthesis Receptors, Estrogen--metabolism Receptors, G-Protein-Coupled--metabolism Tropoelastin--metabolism Up-Regulation