TY - GEN AU - Sun,Qi-Zheng AU - Xu,Yong AU - Liu,Jing-Jing AU - Zhang,Chun-Hui AU - Wang,Ze-Rong AU - Zheng,Ren-Lin AU - Wang,Wen-Jing AU - Li,Lin-Li AU - Yang,Sheng-Yong TI - Structural modification of an EGFR inhibitor that showed weak off-target activity against RET leading to the discovery of a potent RET inhibitor SN - 1573-501X PY - 2015///0113 KW - Drug Discovery KW - ErbB Receptors KW - antagonists & inhibitors KW - Hep G2 Cells KW - Humans KW - Inhibitory Concentration 50 KW - Protein Kinase Inhibitors KW - chemistry KW - Proto-Oncogene Proteins c-ret KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s11030-014-9508-8 ER -