TY - GEN AU - Rigby,Rachel E AU - Webb,Lauren M AU - Mackenzie,Karen J AU - Li,Yue AU - Leitch,Andrea AU - Reijns,Martin A M AU - Lundie,Rachel J AU - Revuelta,Ailsa AU - Davidson,Donald J AU - Diebold,Sandra AU - Modis,Yorgo AU - MacDonald,Andrew S AU - Jackson,Andrew P TI - RNA:DNA hybrids are a novel molecular pattern sensed by TLR9 SN - 1460-2075 PY - 2014///0515 KW - Animals KW - Blotting, Western KW - Dendritic Cells KW - immunology KW - Endosomes KW - Enzyme-Linked Immunosorbent Assay KW - Flow Cytometry KW - Fluorescence Polarization KW - Fluorescent Antibody Technique KW - Humans KW - Immunity, Innate KW - Immunoblotting KW - Mice KW - Mice, Inbred C57BL KW - Models, Immunological KW - Myeloid Differentiation Factor 88 KW - Nucleic Acid Heteroduplexes KW - Real-Time Polymerase Chain Reaction KW - Signal Transduction KW - Toll-Like Receptor 9 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/embj.201386117 ER -