TY  - GEN
AU  - Wang,Xiaowei
AU  - Palasubramaniam,Jathushan
AU  - Gkanatsas,Yannik
AU  - Hohmann,Jan David
AU  - Westein,Erik
AU  - Kanojia,Ruchi
AU  - Alt,Karen
AU  - Huang,Dexing
AU  - Jia,Fu
AU  - Ahrens,Ingo
AU  - Medcalf,Robert L
AU  - Peter,Karlheinz
AU  - Hagemeyer,Christoph E
TI  - Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets
SN  - 1524-4571
PY  - 2014///0616
KW  - Animals
KW  - Blood Platelets
KW  - drug effects
KW  - CHO Cells
KW  - Carotid Arteries
KW  - diagnostic imaging
KW  - Cricetinae
KW  - Cricetulus
KW  - Drug Evaluation, Preclinical
KW  - Fibrinolytic Agents
KW  - adverse effects
KW  - Integrin alpha2
KW  - immunology
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Plasminogen
KW  - metabolism
KW  - Platelet Activation
KW  - Recombinant Fusion Proteins
KW  - genetics
KW  - Single-Chain Antibodies
KW  - Thromboembolism
KW  - drug therapy
KW  - Thrombolytic Therapy
KW  - Ultrasonography
KW  - Urokinase-Type Plasminogen Activator
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1161/CIRCRESAHA.114.302514
ER  -