TY  - GEN
AU  - Gomez,Ingrid
AU  - Benyahia,Chabha
AU  - Louedec,Liliane
AU  - Leséche,Guy
AU  - Jacob,Marie-Paule
AU  - Longrois,Dan
AU  - Norel,Xavier
TI  - Decreased PGE₂ content reduces MMP-1 activity and consequently increases collagen density in human varicose vein
SN  - 1932-6203
PY  - 2014///1108
KW  - Aged
KW  - Collagen
KW  - metabolism
KW  - Dinoprostone
KW  - Female
KW  - Humans
KW  - Hydroxyprostaglandin Dehydrogenases
KW  - Intramolecular Oxidoreductases
KW  - Male
KW  - Matrix Metalloproteinase 1
KW  - Matrix Metalloproteinase 2
KW  - Middle Aged
KW  - Prostaglandin-E Synthases
KW  - RNA, Messenger
KW  - Receptors, Prostaglandin E, EP4 Subtype
KW  - antagonists & inhibitors
KW  - Saphenous Vein
KW  - Tissue Inhibitor of Metalloproteinase-1
KW  - Tissue Inhibitor of Metalloproteinase-2
KW  - Varicose Veins
N1  - Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0088021
ER  -