TY - GEN AU - Loffredo,Francesco S AU - Pancoast,James R AU - Cai,Lei AU - Vannelli,Todd AU - Dong,Jesse Z AU - Lee,Richard T AU - Patwari,Parth TI - Targeted delivery to cartilage is critical for in vivo efficacy of insulin-like growth factor 1 in a rat model of osteoarthritis SN - 2326-5205 PY - 2014///0819 KW - Animals KW - Blood Glucose KW - metabolism KW - Cartilage, Articular KW - drug effects KW - Disease Models, Animal KW - Drug Delivery Systems KW - Heparin KW - Injections, Intra-Articular KW - Insulin-Like Growth Factor I KW - Male KW - Osteoarthritis KW - drug therapy KW - Protein Binding KW - Rats KW - Rats, Inbred Lew KW - Recombinant Fusion Proteins KW - administration & dosage KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/art.38357 ER -