Ricketts, Thomas

A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. [electronic resource] - PloS one 2014 - e85962 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0085962 doi


Adaptor Proteins, Vesicular Transport--metabolism
Alternative Splicing--genetics
Amyotrophic Lateral Sclerosis--genetics
Animals
Behavior, Animal
Body Weight
Codon, Nonsense--genetics
DNA-Binding Proteins--genetics
Embryo Loss--genetics
Ethylnitrosourea
Hand Strength
Hindlimb--metabolism
Homozygote
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Motor Activity
Mutant Proteins--genetics
Phenotype
Point Mutation--genetics
RNA, Messenger--genetics
Superoxide Dismutase
Superoxide Dismutase-1