TY - GEN AU - Megens,Anton A H P AU - Hendrickx,Herman M R AU - Hens,Koen A AU - Fonteyn,Ineke AU - Langlois,Xavier AU - Lenaerts,Ilse AU - Somers,Marijke V F AU - de Boer,Peter AU - Vanhoof,Greet TI - Pharmacology of JNJ-42314415, a centrally active phosphodiesterase 10A (PDE10A) inhibitor: a comparison of PDE10A inhibitors with D2 receptor blockers as potential antipsychotic drugs SN - 1521-0103 PY - 2014///0514 KW - Animals KW - Antipsychotic Agents KW - chemistry KW - Behavior, Animal KW - drug effects KW - Brain KW - Dopamine Antagonists KW - Dopamine D2 Receptor Antagonists KW - Female KW - Guinea Pigs KW - Humans KW - Imidazoles KW - pharmacology KW - Male KW - Motor Activity KW - Phosphodiesterase Inhibitors KW - Phosphoric Diester Hydrolases KW - genetics KW - Prolactin KW - metabolism KW - Protein Binding KW - Pyrazines KW - Rats KW - Rats, Inbred Lew KW - Rats, Sprague-Dawley KW - Rats, Wistar KW - Sf9 Cells KW - Spodoptera KW - Stereotyped Behavior N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/jpet.113.211904 ER -