TY  - GEN
AU  - Mulligan,Christopher M
AU  - Le,Catherine H
AU  - deMooy,Anthony B
AU  - Nelson,Christopher B
AU  - Chicco,Adam J
TI  - Inhibition of delta-6 desaturase reverses cardiolipin remodeling and prevents contractile dysfunction in the aged mouse heart without altering mitochondrial respiratory function
SN  - 1758-535X
PY  - 2014///0813
KW  - Aging
KW  - metabolism
KW  - Animals
KW  - Cardiolipins
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Fatty Acids, Unsaturated
KW  - Heart
KW  - drug effects
KW  - Hydrogen Peroxide
KW  - Linoleic Acid
KW  - Linoleoyl-CoA Desaturase
KW  - antagonists & inhibitors
KW  - Lipid Peroxidation
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mitochondria, Heart
KW  - Models, Biological
KW  - Muscle Contraction
KW  - Myocardium
KW  - Oxygen Consumption
KW  - Piperazines
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/gerona/glt209
ER  -