Mulligan, Christopher M <br/><br/>
Inhibition of delta-6 desaturase reverses cardiolipin remodeling and prevents contractile dysfunction in the aged mouse heart without altering mitochondrial respiratory function.  [electronic resource] 

 -  The journals of gerontology. Series A, Biological sciences and medical sciences  Jul 2014 
 - 799-809 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1758-535X 
<br/><br/><label>Standard No.: </label>10.1093/gerona/glt209  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aging--metabolism<br/>Animals<br/>Cardiolipins--metabolism<br/>Enzyme Inhibitors--pharmacology<br/>Fatty Acids, Unsaturated--metabolism<br/>Heart--drug effects<br/>Hydrogen Peroxide--metabolism<br/>Linoleic Acid--metabolism<br/>Linoleoyl-CoA Desaturase--antagonists & inhibitors<br/>Lipid Peroxidation--drug effects<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Mitochondria, Heart--drug effects<br/>Models, Biological<br/>Muscle Contraction--drug effects<br/>Myocardium--metabolism<br/>Oxygen Consumption--drug effects<br/>Piperazines--pharmacology