Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels. [electronic resource]
- Journal of hematology & oncology Jan 2014
- 4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1756-8722
10.1186/1756-8722-7-4 doi
Acute Disease Adolescent Adult Aged Aged, 80 and over Alternative Splicing Biomarkers, Tumor--genetics Child Child, Preschool CpG Islands--genetics DNA Methylation Female Gene Expression Regulation, Neoplastic HL-60 Cells Hematologic Neoplasms--genetics Humans K562 Cells Leukemia, Myeloid--genetics Male Middle Aged Promoter Regions, Genetic--genetics Reverse Transcriptase Polymerase Chain Reaction U937 Cells WT1 Proteins--genetics Young Adult