TY  - GEN
AU  - Stuart,Emma
AU  - Buchert,Michael
AU  - Putoczki,Tracy
AU  - Thiem,Stefan
AU  - Farid,Ryan
AU  - Elzer,Joachim
AU  - Huszar,Dennis
AU  - Waring,Paul M
AU  - Phesse,Toby J
AU  - Ernst,Matthias
TI  - Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice
SN  - 1538-8514
PY  - 2015///0219
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Blotting, Western
KW  - Cell Proliferation
KW  - Colonic Neoplasms
KW  - genetics
KW  - Cytokine Receptor gp130
KW  - Disease Progression
KW  - Epithelium
KW  - Gastrointestinal Neoplasms
KW  - Gene Expression
KW  - Humans
KW  - Immunohistochemistry
KW  - Janus Kinase 1
KW  - antagonists & inhibitors
KW  - Janus Kinase 2
KW  - Mice, 129 Strain
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mice, Transgenic
KW  - Proliferating Cell Nuclear Antigen
KW  - metabolism
KW  - Pyrazoles
KW  - pharmacology
KW  - Pyrimidines
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - STAT3 Transcription Factor
KW  - Tumor Burden
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1535-7163.MCT-13-0583-T
ER  -