Stuart, Emma <br/><br/>
Therapeutic inhibition of Jak activity inhibits progression of gastrointestinal tumors in mice.  [electronic resource] 

 -  Molecular cancer therapeutics  Feb 2014 
 - 468-74 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-8514 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-13-0583-T  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>Cell Proliferation--drug effects<br/>Colonic Neoplasms--genetics<br/>Cytokine Receptor gp130--genetics<br/>Disease Progression<br/>Epithelium--drug effects<br/>Gastrointestinal Neoplasms--genetics<br/>Gene Expression--drug effects<br/>Humans<br/>Immunohistochemistry<br/>Janus Kinase 1--antagonists & inhibitors<br/>Janus Kinase 2--antagonists & inhibitors<br/>Mice, 129 Strain<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Mice, Transgenic<br/>Proliferating Cell Nuclear Antigen--metabolism<br/>Pyrazoles--pharmacology<br/>Pyrimidines--pharmacology<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>STAT3 Transcription Factor--genetics<br/>Tumor Burden--drug effects