TY - GEN AU - El Maadidi,Souhayla AU - Faletti,Laura AU - Berg,Birgit AU - Wenzl,Christin AU - Wieland,Katrin AU - Chen,Zhijian J AU - Maurer,Ulrich AU - Borner,Christoph TI - A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bak-independent apoptosis SN - 1550-6606 PY - 2014///0325 KW - Adaptor Proteins, Signal Transducing KW - physiology KW - Animals KW - Apoptosis KW - Caspase 3 KW - metabolism KW - Caspase 8 KW - Cytopathogenic Effect, Viral KW - DEAD-box RNA Helicases KW - Enzyme Activation KW - Fas-Associated Death Domain Protein KW - Fibroblasts KW - virology KW - HEK293 Cells KW - HeLa Cells KW - Humans KW - Interferon-Induced Helicase, IFIH1 KW - Mice KW - Mitochondria KW - enzymology KW - Proto-Oncogene Proteins c-bcl-2 KW - RNA Interference KW - RNA, Viral KW - genetics KW - Semliki forest virus KW - Signal Transduction KW - Virus Replication KW - bcl-X Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.1300842 ER -