Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. [electronic resource]
- BMC cancer Jan 2014
- 1 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1471-2407
10.1186/1471-2407-14-1 doi
Animals Breast Neoplasms--enzymology Cell Line, Tumor Cell Proliferation--drug effects Collagen--genetics Collagen Type I--metabolism Collagen Type I, alpha 1 Chain Collagen Type III--metabolism Collagen Type IV--metabolism Disease Progression Enzyme Inhibitors--pharmacology Female Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Humans Kaplan-Meier Estimate Lung Neoplasms--enzymology Mice Mice, SCID Neoplasm Invasiveness Phenotype Procollagen-Proline Dioxygenase--antagonists & inhibitors Prognosis Prolyl Hydroxylases--genetics RNA Interference RNA, Messenger--metabolism Time Factors Transfection Tumor Microenvironment Xenograft Model Antitumor Assays