TY - GEN AU - Shimoyama,Shuji AU - Kasai,Shuya AU - Kahn-Perlès,Brigitte AU - Kikuchi,Hideaki TI - Dephosphorylation of Sp1 at Ser-59 by protein phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole SN - 0006-3002 PY - 2014///0416 KW - Blotting, Western KW - Caco-2 Cells KW - Chelating Agents KW - pharmacology KW - Cytochrome P-450 CYP1A1 KW - genetics KW - Egtazic Acid KW - analogs & derivatives KW - Enzyme Inhibitors KW - Hep G2 Cells KW - Humans KW - MCF-7 Cells KW - Models, Genetic KW - Okadaic Acid KW - Omeprazole KW - Phosphorylation KW - drug effects KW - Polychlorinated Dibenzodioxins KW - Promoter Regions, Genetic KW - Protein Binding KW - Protein Phosphatase 2 KW - antagonists & inhibitors KW - Proton Pump Inhibitors KW - RNA Interference KW - Receptors, Aryl Hydrocarbon KW - Reverse Transcriptase Polymerase Chain Reaction KW - Serine KW - metabolism KW - Sp1 Transcription Factor KW - Transcriptional Activation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bbagrm.2013.12.004 ER -