TY - GEN AU - Bach,Martina P AU - Hug,Eva AU - Werner,Markus AU - Holch,Julian AU - Sprissler,Clara AU - Pechloff,Konstanze AU - Zirlik,Katja AU - Zeiser,Robert AU - Dierks,Christine AU - Ruland,Jürgen AU - Jumaa,Hassan TI - Premature terminal differentiation protects from deregulated lymphocyte activation by ITK-Syk SN - 1550-6606 PY - 2014///0325 KW - Age Factors KW - Animals KW - B-Lymphocyte Subsets KW - immunology KW - Cells, Cultured KW - Chimera KW - Cytokines KW - blood KW - DNA, Complementary KW - genetics KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Hypergammaglobulinemia KW - etiology KW - Inflammation KW - Intracellular Signaling Peptides and Proteins KW - Lymphocyte Activation KW - Lymphopoiesis KW - Lymphoproliferative Disorders KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Oncogene Proteins, Fusion KW - Phosphorylation KW - Positive Regulatory Domain I-Binding Factor 1 KW - Protein Processing, Post-Translational KW - Protein-Tyrosine Kinases KW - Recombinant Fusion Proteins KW - STAT3 Transcription Factor KW - metabolism KW - Syk Kinase KW - T-Lymphocyte Subsets KW - Thymus Gland KW - Transcription Factors KW - biosynthesis KW - Transduction, Genetic KW - Translocation, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.1300420 ER -