Arunachalam, Gnanapragasam <br/><br/>
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1.  [electronic resource] 

 -  British journal of pharmacology  Jan 2014 
 - 523-35 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5381 
<br/><br/><label>Standard No.: </label>10.1111/bph.12496  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylation<br/>Adenylate Kinase--metabolism<br/>Animals<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>Capillaries--cytology<br/>Cellular Senescence--drug effects<br/>Diabetes Mellitus, Type 2--genetics<br/>Endothelium, Vascular--drug effects<br/>Fluorescent Antibody Technique<br/>Forkhead Box Protein O1<br/>Forkhead Transcription Factors--metabolism<br/>Gene Silencing<br/>Hyperglycemia--physiopathology<br/>Hypoglycemic Agents--pharmacology<br/>Metformin--pharmacology<br/>Mice<br/>Mice, Inbred C57BL<br/>Reactive Oxygen Species--metabolism<br/>Signal Transduction--drug effects<br/>Sirtuin 1--genetics<br/>beta-Galactosidase--metabolism