TY - GEN AU - Elagib,Kamaleldin E AU - Rubinstein,Jeremy D AU - Delehanty,Lorrie L AU - Ngoh,Valerie S AU - Greer,Peter A AU - Li,Shuran AU - Lee,Jae K AU - Li,Zhe AU - Orkin,Stuart H AU - Mihaylov,Ivailo S AU - Goldfarb,Adam N TI - Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation SN - 1878-1551 PY - 2014///0220 KW - Actinin KW - genetics KW - Animals KW - Blotting, Western KW - Calpain KW - physiology KW - Cell Differentiation KW - Cell Nucleus KW - Cell Proliferation KW - Cell Transformation, Neoplastic KW - metabolism KW - Cells, Cultured KW - Cytoskeleton KW - Flow Cytometry KW - GATA1 Transcription Factor KW - Humans KW - Immunoprecipitation KW - Leukemia KW - Megakaryocytes KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - Morphogenesis KW - Mutation KW - Positive Transcriptional Elongation Factor B KW - Protein Binding KW - RNA, Messenger KW - Real-Time Polymerase Chain Reaction KW - Reverse Transcriptase Polymerase Chain Reaction KW - Ribonucleoproteins, Small Nuclear KW - Transcription, Genetic N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.devcel.2013.11.013 ER -