TY - GEN AU - Shen,Bo AU - He,Pei-Jie AU - Shao,Chun-Lin TI - Norcantharidin induced DU145 cell apoptosis through ROS-mediated mitochondrial dysfunction and energy depletion SN - 1932-6203 PY - 2014///0728 KW - AMP-Activated Protein Kinases KW - Adenosine Triphosphate KW - metabolism KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Bisbenzimidazole KW - Blotting, Western KW - Bridged Bicyclo Compounds, Heterocyclic KW - Cell Line, Tumor KW - Cell Proliferation KW - Cytochromes c KW - Dose-Response Relationship, Drug KW - Flow Cytometry KW - Humans KW - In Situ Nick-End Labeling KW - Male KW - Membrane Potential, Mitochondrial KW - Micronucleus Tests KW - Mitochondria KW - Proliferating Cell Nuclear Antigen KW - Prostatic Neoplasms KW - drug therapy KW - Reactive Oxygen Species KW - Superoxide Dismutase N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0084610 ER -