Toulany, Mahmoud <br/><br/>
ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition.  [electronic resource] 

 -  Cancer biology & therapy  Mar 2014 
 - 317-28 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1555-8576 
<br/><br/><label>Standard No.: </label>10.4161/cbt.27311  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Carcinoma, Non-Small-Cell Lung<br/>Carcinoma, Squamous Cell<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Clone Cells--drug effects<br/>Drug Synergism<br/>ErbB Receptors--genetics<br/>Erlotinib Hydrochloride<br/>Flavonoids--pharmacology<br/>Furans--pharmacology<br/>Head and Neck Neoplasms<br/>Humans<br/>Lung Neoplasms<br/>Mitogen-Activated Protein Kinase 1--metabolism<br/>Oncogene Protein v-akt--metabolism<br/>Phosphatidylinositol 3-Kinase--metabolism<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins--genetics<br/>Proto-Oncogene Proteins p21(ras)<br/>Pyridines--pharmacology<br/>Pyrimidines--pharmacology<br/>Quinazolines--pharmacology<br/>Signal Transduction--genetics<br/>ras Proteins--genetics