Sun, Qian
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma. [electronic resource]
- Oncology reports Feb 2014
- 933-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1791-2431
Standard No.: 10.3892/or.2013.2917 doi
Subjects--Topical Terms: Animals Apoptosis--genetics Carcinoma, Hepatocellular--genetics Caspase 3--genetics Caspase 9--genetics Cell Line, Tumor Cell Proliferation Cell Transformation, Neoplastic Cyclin D1--biosynthesis Cyclin-Dependent Kinase 4--biosynthesis Cyclin-Dependent Kinase Inhibitor p21--biosynthesis E2F1 Transcription Factor--biosynthesis G1 Phase Cell Cycle Checkpoints--genetics Gene Expression Regulation, Neoplastic Hepatitis B virus--pathogenicity Hepatitis B, Chronic--drug therapy Humans Liver Neoplasms--genetics Male Mice Mice, Inbred BALB C Mice, Nude RNA Interference RNA, Messenger--biosynthesis RNA, Small Interfering Receptor, Notch1--genetics Retinoblastoma Protein--biosynthesis Signal Transduction--genetics Trans-Activators Viral Regulatory and Accessory Proteins Xenograft Model Antitumor Assays