Sun, Qian

Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma. [electronic resource] - Oncology reports Feb 2014 - 933-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1791-2431

10.3892/or.2013.2917 doi


Animals
Apoptosis--genetics
Carcinoma, Hepatocellular--genetics
Caspase 3--genetics
Caspase 9--genetics
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic
Cyclin D1--biosynthesis
Cyclin-Dependent Kinase 4--biosynthesis
Cyclin-Dependent Kinase Inhibitor p21--biosynthesis
E2F1 Transcription Factor--biosynthesis
G1 Phase Cell Cycle Checkpoints--genetics
Gene Expression Regulation, Neoplastic
Hepatitis B virus--pathogenicity
Hepatitis B, Chronic--drug therapy
Humans
Liver Neoplasms--genetics
Male
Mice
Mice, Inbred BALB C
Mice, Nude
RNA Interference
RNA, Messenger--biosynthesis
RNA, Small Interfering
Receptor, Notch1--genetics
Retinoblastoma Protein--biosynthesis
Signal Transduction--genetics
Trans-Activators
Viral Regulatory and Accessory Proteins
Xenograft Model Antitumor Assays