TY - GEN AU - Johnson,Brett E AU - Mazor,Tali AU - Hong,Chibo AU - Barnes,Michael AU - Aihara,Koki AU - McLean,Cory Y AU - Fouse,Shaun D AU - Yamamoto,Shogo AU - Ueda,Hiroki AU - Tatsuno,Kenji AU - Asthana,Saurabh AU - Jalbert,Llewellyn E AU - Nelson,Sarah J AU - Bollen,Andrew W AU - Gustafson,W Clay AU - Charron,Elise AU - Weiss,William A AU - Smirnov,Ivan V AU - Song,Jun S AU - Olshen,Adam B AU - Cha,Soonmee AU - Zhao,Yongjun AU - Moore,Richard A AU - Mungall,Andrew J AU - Jones,Steven J M AU - Hirst,Martin AU - Marra,Marco A AU - Saito,Nobuhito AU - Aburatani,Hiroyuki AU - Mukasa,Akitake AU - Berger,Mitchel S AU - Chang,Susan M AU - Taylor,Barry S AU - Costello,Joseph F TI - Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma SN - 1095-9203 PY - 2014///0123 KW - Antineoplastic Agents, Alkylating KW - adverse effects KW - Brain KW - drug effects KW - Brain Neoplasms KW - drug therapy KW - DNA Helicases KW - genetics KW - DNA Mutational Analysis KW - Dacarbazine KW - Glioma KW - Humans KW - Mutagenesis KW - Neoplasm Grading KW - Neoplasm Recurrence, Local KW - chemically induced KW - Nuclear Proteins KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-akt KW - TOR Serine-Threonine Kinases KW - Temozolomide KW - Transcription Factors KW - Tumor Suppressor Protein p53 KW - X-linked Nuclear Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1239947 ER -