Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. [electronic resource]
- Science (New York, N.Y.) Jan 2014
- 189-193 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1095-9203
10.1126/science.1239947 doi
Antineoplastic Agents, Alkylating--adverse effects Brain--drug effects Brain Neoplasms--drug therapy DNA Helicases--genetics DNA Mutational Analysis Dacarbazine--adverse effects Glioma--drug therapy Humans Mutagenesis--drug effects Neoplasm Grading Neoplasm Recurrence, Local--chemically induced Nuclear Proteins--genetics Proto-Oncogene Proteins B-raf--genetics Proto-Oncogene Proteins c-akt--genetics TOR Serine-Threonine Kinases--genetics Temozolomide Transcription Factors--genetics Tumor Suppressor Protein p53--genetics X-linked Nuclear Protein