Tai, Zhengfu <br/><br/>
Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.  [electronic resource] 

 -  Cellular signalling  Mar 2014 
 - 619-28 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1873-3913 
<br/><br/><label>Standard No.: </label>10.1016/j.cellsig.2013.11.039  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adjuvants, Immunologic--pharmacology<br/>Antibodies--immunology<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival<br/>Colforsin--pharmacology<br/>Cyclic AMP--metabolism<br/>Cyclic AMP-Dependent Protein Kinases--chemistry<br/>GTP-Binding Proteins<br/>HEK293 Cells<br/>HeLa Cells<br/>Hep G2 Cells<br/>Humans<br/>Immunologic Factors--pharmacology<br/>Interferon-alpha--pharmacology<br/>Interferon-beta--pharmacology<br/>Janus Kinase 1--antagonists & inhibitors<br/>Luteolin--pharmacology<br/>Neoplasm Proteins<br/>Phosphodiesterase Inhibitors--pharmacology<br/>Phosphoric Diester Hydrolases--metabolism<br/>Phosphorylation--drug effects<br/>Protein Tyrosine Phosphatase, Non-Receptor Type 11--antagonists & inhibitors<br/>Receptor, Interferon alpha-beta--chemistry<br/>Receptors for Activated C Kinase<br/>Receptors, Cell Surface<br/>STAT1 Transcription Factor--antagonists & inhibitors<br/>STAT2 Transcription Factor--antagonists & inhibitors<br/>Signal Transduction--drug effects<br/>TYK2 Kinase--immunology