TY - GEN AU - Hast,Bridgid E AU - Cloer,Erica W AU - Goldfarb,Dennis AU - Li,Heng AU - Siesser,Priscila F AU - Yan,Feng AU - Walter,Vonn AU - Zheng,Ning AU - Hayes,D Neil AU - Major,Michael B TI - Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination SN - 1538-7445 PY - 2014///0415 KW - Cell Line, Tumor KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - chemistry KW - Kelch-Like ECH-Associated Protein 1 KW - Models, Molecular KW - Mutation KW - NF-E2-Related Factor 2 KW - metabolism KW - Neoplasms KW - genetics KW - Protein Binding KW - Protein Conformation KW - Protein Multimerization KW - Proteolysis KW - Ubiquitination N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-13-1655 ER -