TY - GEN AU - Huijbers,Maartje G AU - Zhang,Wei AU - Klooster,Rinse AU - Niks,Erik H AU - Friese,Matthew B AU - Straasheijm,Kirsten R AU - Thijssen,Peter E AU - Vrolijk,Hans AU - Plomp,Jaap J AU - Vogels,Pauline AU - Losen,Mario AU - Van der Maarel,Silvère M AU - Burden,Steven J AU - Verschuuren,Jan J TI - MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4 SN - 1091-6490 PY - 2014///0224 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Agrin KW - immunology KW - Animals KW - Autoantibodies KW - Cell Line KW - Child KW - Child, Preschool KW - Epitopes KW - Female KW - Humans KW - Immunization, Passive KW - Immunoglobulin G KW - LDL-Receptor Related Proteins KW - antagonists & inhibitors KW - Male KW - Mice KW - Middle Aged KW - Myasthenia Gravis KW - chemically induced KW - Phosphorylation KW - drug effects KW - Protein Multimerization KW - Receptor Protein-Tyrosine Kinases KW - Receptors, Cholinergic KW - Receptors, LDL N1 - Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1313944110 ER -