MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Dec 2013
- 20783-8 p. digital
Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1313944110 doi
Adolescent Adult Aged Aged, 80 and over Agrin--immunology Animals Autoantibodies--immunology Cell Line Child Child, Preschool Epitopes--immunology Female Humans Immunization, Passive Immunoglobulin G--immunology LDL-Receptor Related Proteins--antagonists & inhibitors Male Mice Middle Aged Myasthenia Gravis--chemically induced Phosphorylation--drug effects Protein Multimerization--drug effects Receptor Protein-Tyrosine Kinases--antagonists & inhibitors Receptors, Cholinergic--immunology Receptors, LDL--antagonists & inhibitors