Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates. [electronic resource]
- Molecular neurobiology Jun 2014
- 1200-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1559-1182
10.1007/s12035-013-8591-7 doi
Ataxia Telangiectasia Mutated Proteins--genetics Cells, Cultured DNA Breaks, Double-Stranded--drug effects DNA Repair--drug effects Diphosphonates--pharmacology Female Fibroblasts--drug effects Humans Huntingtin Protein Huntington Disease--genetics Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology Male Mutation--drug effects Nerve Tissue Proteins--genetics