Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex. [electronic resource]
- Molecular and cellular biology Feb 2014
- 348-61 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1098-5549
10.1128/MCB.00825-13 doi
Animals Cells, Cultured Embryo, Mammalian--cytology Fibroblasts--cytology Focal Adhesion Kinase 1--genetics GRB2 Adaptor Protein--genetics Immunoblotting Integrins--metabolism Mice Mice, Knockout Paxillin--genetics Phosphorylation Protein Binding RNA Interference Receptor-Like Protein Tyrosine Phosphatases, Class 4--genetics Signal Transduction Tyrosine--genetics src Homology Domains