Del Nagro, Christopher J
Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. [electronic resource]
- Cell cycle (Georgetown, Tex.) 2014
- 303-14 p. digital
Publication Type: Journal Article
1551-4005
10.4161/cc.27055 doi
Carbolines--pharmacology
Caspases--metabolism
Cell Cycle Proteins--metabolism
Cell Death--drug effects
Cell Line, Tumor
Checkpoint Kinase 1
Chromosomes, Human--genetics
DNA Fragmentation--drug effects
Deoxycytidine--analogs & derivatives
Enzyme Activation
G2 Phase Cell Cycle Checkpoints--drug effects
Humans
Mitosis--drug effects
Nuclear Proteins--metabolism
Protein Kinase Inhibitors--pharmacology
Protein Kinases--metabolism
Protein-Tyrosine Kinases--metabolism
Rad51 Recombinase--metabolism
S Phase Cell Cycle Checkpoints--drug effects
Tumor Suppressor Protein p53--genetics
Gemcitabine