Schmeits, Peter C J

DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells. [electronic resource] - Toxicology letters Jan 2014 - 395-406 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-3169

10.1016/j.toxlet.2013.11.005 doi


Anisomycin--toxicity
Apoptosis--drug effects
Carcinogens--toxicity
Cell Survival--drug effects
Chromosome Mapping
Data Interpretation, Statistical
Endoplasmic Reticulum Stress--drug effects
Gene Expression Profiling
Heat-Shock Proteins--metabolism
Humans
Ionomycin--pharmacology
Jurkat Cells
Microarray Analysis
Mitochondrial Proteins--metabolism
NF-E2-Related Factor 2--metabolism
Nucleic Acid Synthesis Inhibitors--toxicity
RNA, Neoplasm--biosynthesis
T-Lymphocytes--drug effects
Thapsigargin--toxicity
Trialkyltin Compounds--toxicity
Trichothecenes--toxicity