Greineder, Colin F

Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor. [electronic resource] - PloS one 2013 - e80110 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0080110 doi


Acute Lung Injury--immunology
Animals
Antigens, CD--immunology
Cell Line
Endothelial Cells--cytology
Endothelial Protein C Receptor
Endothelium, Vascular--drug effects
Humans
Immunoconjugates--chemistry
Intercellular Adhesion Molecule-1--immunology
Intercellular Junctions--drug effects
Male
Mice
Mice, Inbred C57BL
Molecular Targeted Therapy
Platelet Endothelial Cell Adhesion Molecule-1--immunology
Protein C--agonists
Receptors, Cell Surface--immunology
Single-Chain Antibodies--chemistry
Thrombomodulin--chemistry