TY  - GEN
AU  - Kaindl,U
AU  - Morak,M
AU  - Portsmouth,C
AU  - Mecklenbräuker,A
AU  - Kauer,M
AU  - Zeginigg,M
AU  - Attarbaschi,A
AU  - Haas,O A
AU  - Panzer-Grümayer,R
TI  - Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia
SN  - 1476-5551
PY  - 2014///0430
KW  - Apoptosis
KW  - drug effects
KW  - Child
KW  - Chromatin Immunoprecipitation
KW  - Core Binding Factor Alpha 2 Subunit
KW  - genetics
KW  - Humans
KW  - Imidazoles
KW  - pharmacology
KW  - Piperazines
KW  - Precursor Cell Lymphoblastic Leukemia-Lymphoma
KW  - Proto-Oncogene Proteins c-ets
KW  - Proto-Oncogene Proteins c-mdm2
KW  - Real-Time Polymerase Chain Reaction
KW  - Repressor Proteins
KW  - Signal Transduction
KW  - Transcription, Genetic
KW  - Tumor Suppressor Protein p53
KW  - ETS Translocation Variant 6 Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/leu.2013.345
ER  -