Kaindl, U <br/><br/>
Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia.  [electronic resource] 

 -  Leukemia  Mar 2014 
 - 600-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5551 
<br/><br/><label>Standard No.: </label>10.1038/leu.2013.345  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Child<br/>Chromatin Immunoprecipitation<br/>Core Binding Factor Alpha 2 Subunit--genetics<br/>Humans<br/>Imidazoles--pharmacology<br/>Piperazines--pharmacology<br/>Precursor Cell Lymphoblastic Leukemia-Lymphoma--genetics<br/>Proto-Oncogene Proteins c-ets--genetics<br/>Proto-Oncogene Proteins c-mdm2--genetics<br/>Real-Time Polymerase Chain Reaction<br/>Repressor Proteins--genetics<br/>Signal Transduction<br/>Transcription, Genetic<br/>Tumor Suppressor Protein p53--genetics<br/>ETS Translocation Variant 6 Protein