Morandell, Sandra

A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo. [electronic resource] - Cell reports Nov 2013 - 868-77 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2211-1247

10.1016/j.celrep.2013.10.025 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--genetics
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Cell Proliferation
Cisplatin--pharmacology
DNA Damage--genetics
DNA Repair--genetics
Humans
Intracellular Signaling Peptides and Proteins--genetics
Lung Neoplasms--drug therapy
Mice
Mice, Inbred C57BL
Mice, Transgenic
Protein Serine-Threonine Kinases--genetics
RNA Interference
RNA, Small Interfering
Tumor Suppressor Protein p53--genetics
p38 Mitogen-Activated Protein Kinases--genetics