TY - GEN AU - Clarke,Edward T AU - Williams,Neil A AU - Findlow,Jamie AU - Borrow,Ray AU - Heyderman,Robert S AU - Finn,Adam TI - Polysaccharide-specific memory B cells generated by conjugate vaccines in humans conform to the CD27+IgG+ isotype-switched memory B Cell phenotype and require contact-dependent signals from bystander T cells activated by bacterial proteins to differentiate into plasma cells SN - 1550-6606 PY - 2014///0218 KW - Antigen Presentation KW - Antigens, Bacterial KW - immunology KW - B-Lymphocyte Subsets KW - Bystander Effect KW - Humans KW - Immunoglobulin Class Switching KW - Immunoglobulin G KW - analysis KW - Immunologic Memory KW - Immunophenotyping KW - Leukocytes, Mononuclear KW - Lymphocyte Activation KW - Lymphocyte Cooperation KW - Lymphopoiesis KW - Models, Immunological KW - Neisseria meningitidis, Serogroup C KW - Palatine Tonsil KW - Plasma Cells KW - cytology KW - Polysaccharides, Bacterial KW - Receptors, Antigen, B-Cell KW - T-Lymphocyte Subsets KW - Tetanus Toxoid KW - Tumor Necrosis Factor Receptor Superfamily, Member 7 KW - Vaccines, Conjugate N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.1203254 ER -