TY  - GEN
AU  - Huang,Jingcao
AU  - Wang,Shuiliang
AU  - Lyu,Hui
AU  - Cai,Bo
AU  - Yang,XiaoHe
AU  - Wang,Jianxiang
AU  - Liu,Bolin
TI  - The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells
SN  - 1476-4598
PY  - 2014///0708
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - administration & dosage
KW  - Antibodies, Monoclonal, Humanized
KW  - Antineoplastic Agents
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Cyclin-Dependent Kinase Inhibitor p27
KW  - metabolism
KW  - Drug Resistance, Neoplasm
KW  - Drug Synergism
KW  - Enzyme Activation
KW  - Female
KW  - G1 Phase Cell Cycle Checkpoints
KW  - drug effects
KW  - Humans
KW  - Mice
KW  - Mice, Nude
KW  - Proto-Oncogene Proteins c-akt
KW  - Receptor, ErbB-3
KW  - antagonists & inhibitors
KW  - Signal Transduction
KW  - Trastuzumab
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/1476-4598-12-134
ER  -