Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice. [electronic resource]
- Clinics (Sao Paulo, Brazil) Oct 2013
- 1350-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1980-5322
10.6061/clinics/2013(10)10 doi
Animals Antibiotics, Antineoplastic Anticarcinogenic Agents--pharmacology Bleomycin Carotenoids--pharmacology Collagen Type I--blood Collagen Type I, alpha 1 Chain Collagen Type III--blood Endothelin-1--blood Enzyme-Linked Immunosorbent Assay Female Fibroblasts--drug effects Fibrosis Immunohistochemistry Lung--drug effects Matrix Metalloproteinase 1--blood Mice Mice, Inbred C3H Real-Time Polymerase Chain Reaction Scleroderma, Systemic--chemically induced Skin--drug effects Time Factors Tissue Inhibitor of Metalloproteinase-1--blood Vitamin A--analogs & derivatives