TY  - GEN
AU  - Kovács,Dóra
AU  - Wölfling,János
AU  - Szabó,Nikoletta
AU  - Szécsi,Mihály
AU  - Kovács,Ida
AU  - Zupkó,István
AU  - Frank,Eva
TI  - An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase
SN  - 1768-3254
PY  - 2014///0919
KW  - Androstenes
KW  - chemical synthesis
KW  - Animals
KW  - Antineoplastic Agents
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Cyclization
KW  - Dehydration
KW  - Dose-Response Relationship, Drug
KW  - Drug Screening Assays, Antitumor
KW  - Enzyme Inhibitors
KW  - HeLa Cells
KW  - Humans
KW  - MCF-7 Cells
KW  - Male
KW  - Molecular Conformation
KW  - Oximes
KW  - chemistry
KW  - Rats
KW  - Rats, Wistar
KW  - Steroid 17-alpha-Hydroxylase
KW  - antagonists & inhibitors
KW  - Structure-Activity Relationship
KW  - Testis
KW  - enzymology
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ejmech.2013.10.038
ER  -